Syllabus

Course Code: BP608P    Course Name: Pharmacology III – Practical

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 1. Dose calculation in pharmacological experiments
2 2. Antiallergic activity by mast cell stabilization assay
3 3. Study of anti-ulcer activity of a drug using pylorus ligand (SHAY) rat model and NSAIDS induced ulcer model.
4 4. Study of effect of drugs on gastrointestinal motility
5 5. Effect of agonist and antagonists on guinea pig ileum
6 6. Estimation of serum biochemical parameters by using semi- autoanalyser
7 7. Effect of saline purgative on frog intestine
8 8. Insulin hypoglycemic effect in rabbit
9 9. Test for pyrogens ( rabbit method)
10 10. Determination of acute oral toxicity (LD50) of a drug from a given data
11 11. Determination of acute skin irritation / corrosion of a test substance
12 12. Determination of acute eye irritation / corrosion of a test substance
13 13. Calculation of pharmacokinetic parameters from a given data
14 14. Biostatistics methods in experimental pharmacology( student’s t test, ANOVA)
15 15. Biostatistics methods in experimental pharmacology (Chi square test, Wilcoxon Signed Rank test)
*Experiments are demonstrated by simulated experiments/videos
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