Syllabus

Course Code: BP 308P    Course Name: Pharmaceutical Engineering –Practical

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 I. Determination of radiation constant of brass, iron, unpainted and painted glass.
2 II. Steam distillation – To calculate the efficiency of steam distillation.
3 III. To determine the overall heat transfer coefficient by heat exchanger.
4 IV. Construction of drying curves (for calcium carbonate and starch).
5 V. Determination of moisture content and loss on drying.
6 VI. Determination of humidity of air – i) From wet and dry bulb temperatures –use of Dew point method.
7 VII. Description of Construction working and application of Pharmaceutical Machinery such as rotary tablet machine, fluidized bed coater, fluid energy mill, de humidifier.
8 VIII. Size analysis by sieving – To evaluate size distribution of tablet granulations – Construction of various size frequency curves including arithmetic andlogarithmic probability plots.
9 IX. Size reduction: To verify the laws of size reduction using ball mill and determining Kicks, Rittinger’s, Bond’s coefficients, power requirement and critical speed of Ball Mill.
10 X. Demonstration of colloid mill, planetary mixer, fluidized bed dryer, freeze dryer and such othermajor equipment.
11 XI. Factors affecting Rate of Filtration and Evaporation (Surface area, Concentration and Thickness/ viscosity
12 XII. To study the effect of time on the Rate of Crystallization.
13 XIII. To calculate the uniformity Index for given sample by using Double Cone Blender.
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