Syllabus

Course Code: BP204T    Course Name: Pathophysiology – Theory

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 • Basic principles of Cell injury and Adaptation:
Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,Electrolyte imbalance
• Basic mechanism involved in the process of inflammation and repair:
Introduction, Clinical signs of inflammation, Different types of Inflammation,Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s,Mediators of inflammation,Basic principles of wound healing in the skin,Pathophysiology of Atherosclerosis
2 • Cardiovascular System:
Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial infarction, atherosclerosis and arteriosclerosis)
• Respiratory system: Asthma, Chronic obstructive airways diseases.
• Renal system:Acute and chronic renal failure .
3 • Haematological Diseases:
Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia
• Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones
• Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.
• Gastrointestinal system: Peptic Ulcer
4 • Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease.
• Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout
• Principles of cancer: classification, etiology and pathogenesis of cancer
• Diseases of bones and joints: Rheumatoid Arthritis, Osteoporosis,Gout
• Principles of Cancer:<>/b Classification, etiology and pathogenesis of Cancer
5 • Infectious diseases: Meningitis,Typhoid, Leprosy, Tuberculosis Urinary tract infections
• Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea
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