Syllabus
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Course Code: *Program Elective -II MTBT-113 Course Name: Biosensor Technology |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Introduction: Electrical quantities and units, functional elements of an instrumentation system, static and dynamic characteristics,
principle of analog and digital meters, CRO, energy meters, time and frequency meters, multimeters.
Transducers: Classification, resistive strain gauges, RTD, LVDT, Piezoelectric transducers, Electromagnetic transducers, Optical
transducers, Transducers for biomedical science and their applications. Analytical Instruments: pH meters, radiometric devices, fluorescence spectrophotometers, chromatology (chromatographic techniques- GC and HPLC), electrophoresis, lab on a chip – related instrumentation, Validation, commissioning and maintenance of the above equipments. |
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| 2 | Assay Technologies and Detection methods: Introduction, bioassay design and implementation, radiometric assay, scintillation
proximity assay, fluorescence methodology to cover all types of fluorescence measurements and instrumentation, Reporter gene
assay applications. Bio-analytical applications. Automation and Robotics: Introduction: management and services issues of a centralized robotics HTS (high throughput screening) core, flexible use of people and machines, Bar-code technology and a centralized database, factors for the successful integration of assays, equipment, robotics and software. Perspectives on scheduling |
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| 3 | Data retrival, handling and integration: Database systems, systems integration, data management and tracking
Cardiac and Vascular system: Overview of cardiovascular system, types of blood pressure sensors, Lumped parameters modeling of
a catheter- sensor/system, heart sounds, cardiac catheterization, indirect measurement of blood pressure, measuring blood flow rate,
measuring blood volume, pacemakers, defibrillators, cardiac-assist devices and heart valves- related instrumentation of equipments
and involved sensors. Respiratory system: Modeling the respiratory system, measuring gas flow rate and lung volume, tests of respiratory mechanics, measuring gas concentration, tests of gas transport, ventilators, anesthesia machines- related instrumentation of equipments and involved sensors. |
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| 4 | Biosensors: Introduction to biosensors: concepts and applications, biosensors for personal diabetes management, micro fabricated sensors and the commercial development of biosensors, electrochemical sensors, chemical fibrosensors, Ion-selective FETs, noninvasive blood-gas monitoring, blood-glucose sensors. Noninvasive biosensors in clinical analysis, Applications of biosensors based instruments to the bioprocess industry. Applications of biosensors to the environmental samples, Introduction to biochips and their application to genomics, BIA core- an optical biosensors | |
