Syllabus
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Course Code: B-ZOO-402 Course Name: Animal Genetics |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | 1. Elements of Heredity and variations. 2. The varieties of gene interactions 3. Linkage and recombination: Coupling and repulsion hypothesis, crossing-over and chiasma formation; gene mapping. 4. Sex determination and its mechanism: male and female heterozygous systems, genetic balance system; role of Y-chromosome, male haploidy, cytoplasmic and environmental factors, role of hormones in sex determination. 5. Sex linked inheritance: Haemophilia and colour blindness in man, eye colour in Drosophila, Non-disjunction of sex-chromosome in Drosophila, Sex-linked and sex-influenced inheritance 6. Extra chromocomal and cytoplasmic inheritance: i) Kappa particles in Paramecium ii) Shell coiling in snails iii) Milk factor in mice |
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| 2 | 7. Multiple alleslism: Eye colour in Drosophila; A, B, O blood group in man. 8. Human genetics: Human karyotype, Chromosomal abnormalities involving autosomes and sex chromosomes, monozygotic and dizygotic twins. 9. Inborn errors of metabolism (Alcaptonuria, Phenylketonuria, Albinism, sickle-cell anaemia). 10. Nature and function of genetic material: Structure and type of nucleic acids; Replication and Protein synthesis. 11. Eugenics, euthenics and euphenics; spontaneous and induced (chemical and radiations) mutations; gene mutations; chemical basis of mutations; transition, transversion, structural chromosomal aberrations (deletion, duplication, inversion and translocation); Numerical aberrations (autoploidy, euploidy and polyploidy in animals) 12. Applied genetics: genetic counseling, pre-natal diagnosis, DNA-finger printing, transgenic animals. |
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