Syllabus

Course Code: DSES2-518    Course Name: Bio-Statistics

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 Introduction to epidemiology, principles of epidemiologic investigation, Epidemiologic measures. Design and analysis of epidemiologic studies: types of studies, case-control studies, cohort studies, quantitative methods in screening
2 Introduction of clinical trials: Definition and type of trials, phases of clinical trials, designs of randomized controlled clinical trial (RCT), the need and ethics of clinical trials, overview of Phase I – IV trials, multicenter trials. Estimation and importance of sample size in research design.
3 Planning Research and Data Generation: Research design, Primary and secondary data; Making survey-questionnaire, Data collection methods and arrangement; analysis of data using different study designs using statistical software like SPSS and R. National Sample survey, survey sampling and its methods.
4 SURVIVAL ANALYSIS: life table techniques, estimation of survival function – actuarial estimator, Kaplan – Meier estimator, total time on test, estimation under the assumption of IFR/DFR, tests of exponentiality against hazard function; Ageing classes( IFR,IFRA,NBU,NBUE) and their properties, Dual classes .
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