Syllabus
|
Course Code: CHEM-501-II Course Name: Bio-organic Chemistry |
||
| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
|---|---|---|
| 1 | Nucleic Acids Components of Nucleic acids: Adenine, guanine, thymine and Cytosine (Structure only), other components of nucleic acids, Nucleosides and nucleotides (nomenclature), Structure of polynucleotides; Structure of DNA (Watson-Crick model). Peptides and Proteins Structural and functional classification of proteins. Primary & Secondary structures of peptides and proteins, Tertiary and Quaternary structure of proteins. Synthesis of simple peptides (upto dipeptides) by N-protection (t-butyloxycarbonyl and phthaloyl) & C-activating groups and Merrifield solid phase synthesis. |
|
| 2 | Lipids Introduction to lipids and their classification. Waxes-Introduction, structure and functions of bees wax, wool Wax, spermaceti wax, carnauba wax. Fatty acid classification-cis and trans fatty acid, saturated and unsaturated fatty acid, Essential fatty acids and their functions, Structure and functions of triacylglycerol and sphingolipids. Fluid mosaic model of cell membrane. Concept of Energy in Biosystems Calorific value of food. Standard caloric content of carbohydrates, proteins and fats. Oxidation of foodstuff (organic molecules) as a source of energy for cells. Introduction to Metabolism (catabolism, anabolism), ATP: the universal currency of cellular energy, ATP hydrolysis and free energy change. |
|
