Syllabus
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Course Code: BOT502 Course Name: Molecular Biology |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Genetic material DNA: Miescher to Watson and Crick- historic perspective,
Griffith’s and Avery’s transformation experiments, Hershey-Chase bacteriophage experiment.
DNA structure, types of DNA, types of genetic material. DNA Replication: Prokaryotes and eukaryotes; bidirectional replication, semi–conservative, semi discontinuous RNA priming, Ǿ (theta) mode of replication, replication of linear, dsDNA, replicating the 5 ́end of linear chromosome including replication enzymes. |
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| 2 | Transcription: Prokaryotes and Eukaryotes. Types of structures of RNA (mRNA, tRNA, rRNA), RNA polymerase- various types; Translation: Prokaryotes and eukaryotes, genetic code. Regulation of gene Expression in Prokaryotes: Lac operon and Tryptophan operon; regulation of gene expression in Eukaryotes. |
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