Syllabus
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Course Code: B-BCH-501 Course Name: Immunology-I |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Introduction to immune system: Historical Perspective, Cells and organs of the immune
system; primary and secondary lymphoid organs; bone marrow, thymus, spleen, lymphnodes
and tissues (MALT) Components of immunity: Innate immunity- Anatomic, physiological, phagocytic and inflammatory barriers; Adaptive immunity- A brief account of the functions of Humoral and cell-mediated immune responses. Primary and secondary immune responses, connection between innate and adaptive immunity, cell adhesion molecules, chemokines, leukocyte extravasation, localized and systemic response Antigens: Antigens and haptenes, Immunogenicity versus antigenicity, factors influencing immunogenicity; Adjuvants; Epitopes (properties of B-Cell and T-cell epitopes) |
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| 2 | Immunoglobulins: Structure, distribution of classes and subclasses of immunoglobulins,
physicochemical properties of different classes of immunoglobulins, antigenic determinants on
immunoglobulins and Ig superfamily Monoclonal Antibodies: Introduction, formation and selection of hybrid cells, their production and applications. Biology of B lymphocytes: Antigen independent phase of B cell maturation and selection, humoral response- Thymus dependent and Thymus independent response, anatomical distribution of B-cell population |
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