Syllabus
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Course Code: B-BCH-101 Course Name: Molecules of life-I |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Water and Buffers: Structure, hydrogen bonding, solvent properties, and ionization, Fitness of
the aqueous environment for living organisms, Weak acids and bases,ionization of weak acids,
titration of weak acid by a strong base, pH, buffers, Henderson-Hasselbalch equation and
physiological buffers; phosphate, bicarbonate, amino acid, protein, hemoglobin buffer system Carbohydrates: Definition and classification. Monosaccharides: Structure, occurrence and biological importance of common monosaccharides; Stereoisomerism of sugars; Killani cyanohydrins synthesis, Mutarotation; Reactions: oxidation, reduction, periodic acid oxidation, reactions with hydrazine, hydroxylamine, action of acids & alkalies, formation of glycosides and esters. Important derivatives of monosaccharides: deoxy sugars and amino sugars. Structure, occurrence and functions of important di- and trisaccharides. Polysaccharides: Structure, occurrence and biological importance of starch, glycogen, cellulose, chitin, pectins, glycosaminoglycans & proteoglycans. |
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| 2 | Lipids: Definition and classification. Fatty acids: introduction, classification, nomenclature, structure and properties of saturated and unsaturated fatty acids. Essential fatty acids. Waxes, Triacylglycerols: physical and chemical properties. Characterization of fats: Saponification values, iodine value, rancidity of fats, Reichert-Meissel number, peroxide value. Reactions of glycerol. Biological significance of fats. Structure & biological functions of glycerophospholipids (lecithin, cephalin, phosphatidylserine, phosphatidylinositol, plasmalogens), sphingolipids and glycolipids (cerebrosides and gangliosides), Structure & biological functions of steroids (cholesterol, ergosterol, lanosterol, bile acids. Structure, properties and functions of isoprenoids (-carotene, α-carotene) and prostaglandins. |
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