Syllabus
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Course Code: DSE* Anthropology (i) B-ANTH-502(i) Course Name: Human Population Genetics |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | 1. Definition and concept of population genetics,History of population genetics,Genotype &allel
frequencies,Mating system. 2. Mendelian inheritance in man. Mode of inheritance – Autosomal, sex linked, sexinfluenced, sex limited, lethal, sub-lethal andPolygenic inheritance in man. 3. Non Mendelian inheritance in man, Types: Extranuclear, gene conversion, infectiousheredity, genomic imprinting, Mosaicism, Trinucleotide repeat disorders. |
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| 2 | 1. Population Genetics and the Hardy Weinberg Law human variation. Causes and changes inthe
gene frequency – mutation, isolation, migration, selection, inbreeding and geneticdrift.
Consanguineous and non- consanguineous mating genetic load, genetic effect ofconsanguineous
and cousin marriages, genetic adaptation. 2. Other complicating factors in human genetics, like age of onset, variable expressivity,penetrance, uniparental disomy, genomic imprinting. |
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