Syllabus
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Course Code: B-BCH-602 Course Name: Clinical Biochemistry-II |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Nutritional disorders Overview of major and minor nutrient components in the diet. Balanced diet and the concept of RDA. Nutrient deficiencies; Kwashiorkor and Marasmus, Scurvy, beri beri, pellagra and B12 deficiency, Xerophthalmia and Night blindness, Vitamin D deficiency, Vitamin K deficiency. Lifestyle disorders Obesity, Type-2-Diabetes mellitus, Cardio vascular disorders and Thyroidism. Irritable bowel syndrome- biochemistry behind the disorder and the influence of diet, stress and environment on the condition |
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| 2 | Multifactorial complex disorders and Cancer Understanding the definition of multifactorial diseases. Polygenic diseases and the relationship of environmental factors and genetic makeup in the onset of diseases; Cancer, Parkinson’s disease, ALS, Skeletal muscle atrophy Diseases due to misfolded proteins Introduction to protein folding and proteosome removal of misfolded proteins; etiology and molecular basis for Alzheimer's, sickle cell anemia, Thalassemia. Pandemic and epidemic diseases: Pandemic versus epidemic diseases; history, causative agents and pathogenesis of Chikungunya, Cholera, Ebola virus disease, Novel coronavirus (2019-nCoV), Smallpox, Yellow fever, Zika virus disease, Polio |
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