Syllabus

Course Code: BS-101    Course Name: Chemistry

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 Atomic and molecular structure (10 lectures)
Molecular orbitals of diatomic molecules (N2, O2, CO) Equations for atomic and molecular orbitals. Energy level diagrams of diatomics. Pi-molecular orbitals of butadiene and benzene and aromaticity. Crystal field theory and energy level diagrams of [Co(NH3)6], [Ni(CO)4], [PtCl2(NH3)2] and magnetic properties of metal complexes. Band structure of solids and the role of doping on band structures.
2 Spectroscopic techniques and applications (8 lectures)
Principles of spectroscopy and selection rules. Electronic spectroscopy (basic concept). Fluorescence and its applications in medicine. Vibrational and rotational spectroscopy of diatomic molecules. Applications. Basic concepts of Nuclear magnetic resonance and magnetic resonance imaging, Diffraction and scattering.
3 Use of free energy in chemical equilibria (4 lectures)
Thermodynamic functions: energy, entropy and free energy. Estimations of entropy and free energies. Free energy and emf. Cell potentials, the Nernst equation and applications.
Periodic properties (4 Lectures)
Effective nuclear charge, penetration of orbitals, variations of s, p, d and f orbital energies of atoms in the periodic table, electronic configurations, atomic and ionic sizes, ionization energies, electron affinity and electronegativity, polarizability, oxidation states, coordination numbers and geometries, hard soft acids and bases, molecular geometries (H2O, NH3, PCl5, SF6, CCl4, Pt(NH3)2Cl2
4 Stereochemistry (6 lectures)
Representations of 3 dimensional structures, structural isomers and stereoisomers, configurations and symmetry and chirality, enantiomers, diastereomers, optical activity, absolute configurations and conformational analysis.
Organic reactions and synthesis of a drug molecule (4 lectures)
Introduction to reactions involving substitution, addition, elimination, oxidation, reduction, cyclization and ring openings. Synthesis of a commonly used drug molecule(paracetamol and Aspirin)
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