Syllabus

Course Code: CHEM 403    Course Name: Inorganic Chemistry Special-V

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 Metal Storage Transport and Biomineralization
Ferritin, transferrin, and siderophores.
Calcium in Biology
Calcium in living cells, transport and regulation, molecular aspects of intramolecular processes, extra cellular binding proteins, Coenzyme vitamin B12, vitamin B6.
2 Metalloenzymes
Zinc enzymes – carboxypeptidase and carbonic anhydrase, alkaline phosphatase and alcohol dehydrogenase, Copper enzymes – superoxide dismutase. Molybdenum oxatransferase enzymes – xanthine oxidase.
3 Supramolecular Chemistry
Concepts and language.
a) Molecular recognition: Molecular receptors for different types of molecules including anionic substrates, design and synthesis of co-receptor molecules and multiple recognition.
b) Supramolecular reactivity and catalysis.
c) Transport processes and carrier design.
d) Supramolecular devices. Some example of self-assembly in supramolecular Chemistry.
4 Principles of Bio-Inorganic Medicine
Evaluation of modern therapeutical, means of administering chemicals to humans, concentration effects, and dose-response relationship, future developments and trends in bio-inorganic therapy.
Metals in Medicine
Metal deficiency and disease, toxic effects of metals, metals used for diagnosis and chemotherapy with particular reference to anticancer drugs.
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