Syllabus
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Course Code: CHEM 104c Course Name: Introduction to pharmacy and pharmacology |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Introduction Introduction to Pharmaceutical sciences, its branches, naming of drugs, Generic drugs, routes of drug administration, drug development and its regulation. Introduction of pharmacopeia (IP, BP, USP), introduction of national formularies, typical parts of monograph of Indian pharmacopeia, an introduction to content of IP. Dosage Forms-1 Solid dosage forms: Tablets-Types, granulation, compression, additives used in formulations, coating, evaluation (including dissolution, disintegration, Hardness, Friability, weight variation). Capsules-Soft and hard gelatin capsules, microencapsulation. |
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| 2 | Dosage Forms-II Semi solid dosage forms: Introduction, types, brief description of ointments and creams. Biphasic liquid dosage forms: Emulsions and suspensions-types, formulation, methods of preparation, stability. Monophasic liquid dosage forms: Types, brief description of mixtures and syrups. Sterile dosage forms and ophthalmic products. Toxicology Introduction, acute and chronic toxicity, LD50 and ED50, therapeutic index, adverse drug effects, dose response relationship, therapeutic drug monitoring, General principles of management of poisoning, antidotes, Treatment of heavy metal poisoning and drugs (barbiturates, benzodiazepines, salicylates, morphine & morphine derivatives, alcohol). |
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| 3 | Pharmacokinetics Physicochemical factors in transfer of drugs across membranes, ADME (Absorption, distribution, metabolism-Phase I and Phase II reactions, Excretion) of drugs, important pharmacokinetic parameters-apparent volume of distribution, bioavailability, clearance, Half life. Pharmacodynamics Mechanism of drug action, drug targets, neurotransmitters and hormones, the receptor role, Drug Receptor Interactions, types of receptors, structure and functioning of ion channel receptors, G-protein coupled receptors, kinase-linked receptors. Course outcomes: The paper is designed to provide basic knowledge about pharmacology, naming, routes to administer, pharmacopoeias, dosage forms, toxicology, pharmacokinetics and pharmacodynamics. |
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