Syllabus
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Course Code: CHEM 104b Course Name: Chemistry of Life Science |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Carbohydrates Structure and biological functions of important monosachharides (excluding detailed conformational analysis) and derivatives of monosaccharides like glycosides, deoxy sugars, myoinositol, amino sugars-N-acetylmuramic acid and sialic acid. Disaccharides- sucrose, lactose and maltose. Structure and biological functions of Structural polysaccharides (cellulose and chitin) and Storage polysaccharides (starch and glycogen) Heteropolysaccharides-glucosaminoglycans/mucopolysaccharides. Glycoconjugates- glycoproteins and glycolipids. Role of sugars in biological recognition. Blood group substances. Cell Structure and Metabolism Structure of prokaryotic and eukaryotic cells, intracellular organelles and their functions, comparison of plant and animal cells. Overview of metabolic processes - catabolism and anabolism. ATP - the biological energy currency. Carbohydrate metabolism: glycolysis and Kreb's cycle. |
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| 3 | Nucleic Acids and Genetic Code Structure and functions of nucleotides, nucleosides, DNA (Watson-Crick model, Chargaff’s rules) and RNA (m RNA, r-RNA and t-RNA). Genetic code and its characteristics, codon-anticodon pairing (Wobble hypothesis). Replication, Transcription and Translation (Prokaryotes only) Replication of DNA: Maselson-Stahl experiment, mechanism of replication (Initiation, Elongation and Termination). Transcription: Promoters site, Initiation, Elongation, Termination. Translation: Activation of amino acids, Initiation, Elongation, Termination. |
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