Syllabus
|
Course Code: BT-403 Course Name: Animal and Medical Biotechnology |
||
| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
|---|---|---|
| 1 | Animal Cloning Concept of animal cloning, cloning from embryonic and adult cells, Creation of Dolly, Molly and Polly Transgenic Animals Transfection methods-DNA microinjection, Retroviral and embryonic stem cell methods, Application of transgenic animals-mice, sheep, pigs, goats, cows, fish |
|
| 2 | Embryo transfer Technology Superovulation and embryo transfer in cattle, artificial insemination, advantages of embryo transfer Stem Cell Technology Definition and meaning of stem cells, function, adult and embryonic stem cells, hematopoietic, mesenchymal and neural stem cells, therapeutic cloning for embryonic stem cells, ethical issues. |
|
| 3 | Nucleic Acid Therapeutics -Antisense RNA, Ribozyme, Aptamers, DNAzymes, RNAi, Zinc Finger Nucleases Protein Therapeutics-Pharmaceuticals (Tumour Necrosis Factor, Human Growth Hormone, Interferon etc), Recombinant Antibodies (Human Monoclonal Antibodies, Hybrid Human- Mouse Monoclonal Antibody, Anticancer Antibodies), Enzymes (DNase, Alginate Lyase, Alpha 1 Antitrypsin, Phenyl Ammonia Lyase, Glycosidases); Use of Lactic Acid Bacteria for delivery of therapeutic agents (Interleukin-10, Leptin, An HIV Inhibitor, Insulin) Gene Therapy-Types of gene therapy, Augmentation Gene therapy, Targeted gene therapy, gene therapy for SCID, Cancer, Neurological disorders, Ethical issues |
|
| 4 | Nanobiotechnology- Introduction, types and synthesis of Nanoparticles, Protein based nanostructures, applications of nanoparticles – Nanobiosensors, drug and gene delivery, disease diagnostics and therapy; risk potential of nanomaterials Pharmacogenomics-concept, Role of Genetic Variations in different responses of individuals to drugs, Pharmacogenomics and industry, personalized Medicine, DNA fingerprinting in Forensic sciences |
|
