Syllabus
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Course Code: BCH-404A Course Name: Basics of Microbiology |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | Members of the microbial world; Impact of microorganisms on humans; Gram+veandGram–vebacteria;Controlofmicroorganismsby physical & chemical agents; Nutritional types of microorganisms; Culture media; Pure culture techniques; Microbial Growth curve, Continuous culture of microorganisms; influence of environmental factors on growth: solutes and water activity, pH, temperature, oxygen concentration, pressure and radiations; Biofilms |
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| 2 | Bacterial Genetics: Transformation, Transduction &Conjugation
Fermentations: Lactic and mixed acid fermentations; Amino acid fermentation by Clostridium species and the Stickland reaction; fermentations without substrate level phosphorylation; Fermentors; Characteristics of large scale fermentations; Major products of industrial microbiology: Antibiotics (penicillin and tetracyclines), Alcohol and alcoholic beverages, Organic compounds (citric acid); Yeast as a food and food supplement; Microbes as products: Biosensors and Bioinsecticides Methods of food preservation; Food born infection and intoxications (Salmonella & Staphylococcus) |
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| 3 | Biochemical activities of Microorganisms: Extracellular enzymatic activities of microorganisms, Carbohydrate fermentation, Triple sugar-iron agar test, IMViC test, Hydrogen sulphide test, Urease test, Litmus milk reactions, Nitrate reduction test, Catalase test, Oxidase test, Utilization of amino acids Acetogenesis; Methanogenesis; Microbial Biodegradation of Petroleum and Xenobiotics; Biodegradable plastics Virus: Structure and general characteristics; cultivation of viruses; Viroids and Prions |
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| 4 | Microbial diseases and their control:
Pathogenicity of microorganisms: Host-parasite interactions; pathogenesis of viral diseases; Bacterial pathogenesis; pathogenicity islands; Toxigenicity: General characteristics of Exotoxins and Endotoxins Antimicrobial chemotherapy: General Characteristics of antimicrobial drugs, Mechanism of action of antibacterial drugs: inhibitors of cell wall synthesis, protein synthesis inhibitors, metabolic antagonists, nucleic acid synthesis inhibitors; factors influencing antimicrobial dug effectiveness, Mechanisms of drug resistance; Mechanism of action of Antifungal drugs and Antiviral drugs |
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