Syllabus

Course Code: BCH-304B    Course Name: Human Physiology

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 Gastrointestinal Physiology: Secretory functions of the alimentary tract: General principles of alimentary tract secretion; Basic mechanism of stimulation of alimentary tract glands; Basic mechanism of secretion by glandular cells; Lubricating and protective properties of mucus and importance of mucus in gastrointestinal tract; Composition, function and regulation of saliva, gastric, pancreatic, intestinal and bile secretions. Digestion and absorption of carbohydrates, lipids and proteins
2 Respiration: Components of respiratory system and their functions; transfer of blood gases- O2 and CO2; Bohr effect; role of chloride ions in oxygen transport; effect of 2,3-BPG on O2 affinity of Hb; Clinical importance of 2,3-BPG.
Acid Base Balance: Acid base balance; Role of blood buffers; respiratory and renal mechanism in the maintenance of blood pH;
Excretory System: Structure of nephron; formation of urine; tubular re-absorption of glucose, water and electrolytes; tubular secretion; regulation of water and electrolyte balance; role of kidneys and hormones in their maintenance.
3 General principles of nervous system: Structure of a neuron, resting potential, action potential, propagation of action potentials as an impulse; types of synapses; role of Ca+2 in release of neurotransmitter from pre-synaptic membrane; function of receptor proteins and secondary messenger on the postsynaptic neuron; Characteristics of some important neurotransmitters (Dopamine, GABA, Glutamate, Acetylcholine, Serotonin, NO).
Blood Cells and Blood Clotting: Blood components and their function; plasma proteins; blood coagulation.
4 Hormones: Classification and mechanism of action, physiological functions, regulation of growth hormones, ADH, oxytocin, thyroid hormones, mineralocorticoid, glucocorticoid, insulin, glucagon, parathyroid hormone, and male and female reproductive hormones.
Biosignaling: General features of signal transduction, G protein-coupled receptors and Second messengers (cAMP, diacyl glycerol, inositol triphosphate and Ca 2+ ions), receptor tyrosine kinases
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