Syllabus
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Course Code: M-Z 404 Course Name: Molecular Reproduction– II |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | 1. Sex Determination: Chromosomal sex determination in mammals, Autosomal testis determining genes, Hormonal regulation of sex determination. Androgen insensitivity syndrome 2. Reproductive cycles: Menstrual cycle and its regulation in humans, Estrous cycle in rat, Estrous behaviour in cycling animals. 3. Molecular bases of Fertilization in mammals: Gamete transport, fertilization competence by gametes, capacitation, acrosome reaction, oocyte-sperm interaction, oocyte activation, gamete fusion. |
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| 2 | 4. Hormonal regulation: Implantation, pregnancy, parturition, oxytocin- synthesis, secretion and its role in parturition, placenta and its hormones. 5. Mammary glands- Structure, development and physiology of lactation, milk synthesis and secretion; regulation and ejection of milk. |
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| 3 | 6. Apoptosis: Molecular mechanism, regulation, and significance; Apoptosis in reproductive aging. 7. Assisted reproductive techniques- IVF, IUI, ICSI, GIFT, ZIFT, Surrogacy, negative aspects and recent trends in ART. 8. Contraception: Natural method (Fertility awareness), Surgical, Physical/Barrier methods, Chemical methods, Immunocontraception. |
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| 4 | 9. Reproductive failure in females-Ovarian dysfunction, estrus abnormalities, fertilization failure, Pregnancy wastage- embryonic mortality, fetal mortality, infectious and non-infectious causes, prenatal and neonatal mortality. 10. Reproductive failure in males-Congenital malformations-cryptorchidism, testicular hypoplasia, ejaculatory disturbances, sperm defects, fertilization failure. | |
