Syllabus

Course Code: M-Z 403    Course Name: Environmental Toxicology

MODULE NO / UNIT COURSE SYLLABUS CONTENTS OF MODULE NOTES
1 1.0 Introduction to Environmental Toxicology:
1.1 Emergence of toxicity in the environment
1.2 Classical toxicology, ecotoxicology and environmental toxicology.
1.3 Classification of toxicants.
2.0 Toxic agents: Pesticides, metals, solvents radiation, carcinogens, poisons, bio-toxins, petrochemicals.
2 3.0 Toxicant uptake:
3.1 Route of toxicant uptake/Absorption of toxicant at tissue and cellular level
3.2 Distribution and storage of toxicant.
3.3 Biotransformation and elimination of toxicant.

4.0 Xenobiotics: Definition, types and significance Target organ toxicity:
4.1 Hematotoxicity
4.2 Hepatotoxicity
4.3 Nephrotoxicity
4.4 Neurotoxicity
3 5.0 Environmental Toxicology: Food additives, air, water and soil pollutants and Bioindicators.
6.0 Effect of pollutant on ecosystem with case study of important Organo-phosphorous and Organo-chlorine pesticides and Nitrates
7.0 Solid waste management: Primary waste products-Solid waste, toxic biological and hospital landfills, incineration, source reduction and recycling.
4 8.0 Bioremediation, its role and significance.
9.0 Toxicological risk assessment and management with reference to relevant case study.
10.0 Principles and significance of systematic toxicology.
11.0 Genotoxicology: Definition, Effects, molecular mechanisms and prevention.
12.0 Applications of toxicology anthropogenic activities and environment.
13.0 Human toxicology and medicinal ethics.
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