Syllabus
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Course Code: M-Z 401 Course Name: Developmental Biology |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | 1 Introduction to animal development: 1.1 Problems of developmental biology 1.2 Developmental patterns in metazoans 1.3 Development in unicellular eukaryotes 1.4 Development in Dictyostelium 2. Creating multicellularity: 2.1 Cleavage types and significance, Blastula, Fate maps, cell lineages 2.2 Comparative account of gastrulation 3. Early vertebrate development: 3.1 Neurulation and ectoderm 3.2 Mesoderm and endoderm |
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| 2 | 4. Cytoplasmic determinants and autonomous cell specification: 4.1 Cell commitment and differentiation 4.2 Germ cell determinants 4.3 Germ cell migration 4.4 Progressive cell - Cell interaction and cell specification fate 4.5 Cell specification in nematodes 5. Body pattern formation: 5.1 Establishment of Body axis in mammals and birds 5.2 Proximate tissue interactions 5.3 Genetics of axis specification in Drosophila |
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| 3 | 6. Hormones as mediators of development: 6.1 Amphibian metamorphosis 6.2 Insect metamorphosisv 7. Biology of sex determination: 7.1 Chromosomal sex determination – Mammals, Drosophila and Nematodes 7.2 Testis determining genes 7.3 Secondary sex determination in mammals 7.4 Environmental sex determination. 8. Cell death and cell renewal 8.1 Programmed cell death 8.2 Stem cells and the maintenance of adult tissues 8.3 Embryonic stem cells and therapeutic cloning |
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| 4 | 9 Environmental evolution and animal development 9.1 Environmental cues and effects 9.2 Malformations and disruptions 9.3 Changing evolution through development modularity 9.4 Developmental constraints 10. Homeobox concept in different phylogenetic groups 10.1 Cell diversification in early animal embryo 10.2 Tetrapod limb development 10.3 Skeletal muscle regeneration 10.4 Connective tissue cell family 10.5 Blood cells formation |
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