Syllabus
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Course Code: M-Z 304 Course Name: Molecular Reproduction-I |
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| MODULE NO / UNIT | COURSE SYLLABUS CONTENTS OF MODULE | NOTES |
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| 1 | 1. Male Reproductive system: Cytology of testis and spermatozoon, physiology of spermatogenesis, molecular bases of testicular steroidogenesis, endocrine regulation of steroidogenesis, role of male accessory sex structures. 2. Female Reproductive System: Structural and histochemical aspects of ovary and primordial follicles. 3. Folliculogenesis: Dynamics of follicular growth and maturation, intracellular dynamics of cholesterol synthesis-two cell theory, endocrine regulation of folliculogenesis. |
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| 2 | 4. Oocyte Maturation- Nuclear, epigenetic and cytoplasmic; oocyte granulosa interactions 5. Ovulation- Mechanism, Induced and spontaneous ovulators. 6. Corpus Luteum- Structure and functions, molecular mechanism and endocrine regulation of luteinization, luteal steroidogenesis, corpus luteum of pregnancy. |
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| 3 | 7. Follicular atresia: Causes, regulation and significance, factors affecting atresia, role of granulosa cells apoptosis in atresia. 8. Male sterility- Azoospermia, Oligozoospermia, Asthenozoospermia, Varicocele, Genetic basis for male infertility. 9. Female infertility- genetic and endocrinal factors, PCOD, atresia. |
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| 4 | 10. Female reproductive aging: epidemiology, theories, markers, significance, implications, fertility preservation. 11. Age-Related Reproductive disorders- perimenopause, premenopause, post menopausal disorders, osteoporosis. 12. Effect of diet, nutrition, stress, disease, exercise and yoga on reproductive ageing. |
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